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Inhibitors of sterol synthesis. Effect of dietary 5α-cholest-8(14)-EN-3β-OL-15-one on acat activity of jejunal microsomes of the rat

✍ Scribed by Dolores H. Needleman; Kerry Strong; Katherine A. Stemke; John S. Brabson; Alemka Kisic; George J. Schroepfer Jr.

Book ID
117057575
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
337 KB
Volume
148
Category
Article
ISSN
0006-291X

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## Abstract Oxidation of 5α‐cholest‐8(14)‐ene‐3β,7α,15α‐triol with silver carbonate‐celite gave 5α‐cholest‐8(14)‐ene‐7α,15α‐diol‐3‐one in 88% yield. Treatment of the latter compound with tritiated water under basic conditions gave a labeled product which was reduced with lithium tri‐__tert__‐butoxy