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Inhibition of p53 function diminishes androgen receptor-mediated signaling in prostate cancer cell lines

✍ Scribed by Cronauer, Marcus V; Schulz, Wolfgang A; Burchardt, Tatjana; Ackermann, Rolf; Burchardt, Martin


Book ID
110068426
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
183 KB
Volume
23
Category
Article
ISSN
0950-9232

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## Abstract The androgen receptor (AR) is a ligand‐dependent transcription factor belonging to the steroid hormone receptor superfamily. Under normal conditions, in the absence of a ligand, the AR is localized to the cytoplasm and is actively transported into the nucleus upon binding of androgens.