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Regulator of G-protein signaling 2 (RGS2) inhibits androgen-independent activation of androgen receptor in prostate cancer cells

โœ Scribed by Cao, X; Qin, J; Xie, Y; Khan, O; Dowd, F; Scofield, M; Lin, M-F; Tu, Y


Book ID
110070429
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
529 KB
Volume
25
Category
Article
ISSN
0950-9232

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## Abstract Regulator of Gโ€protein signalingโ€2 (RGSโ€2) belongs to a novel family of GTPaseโ€activating proteins that rapidly turnโ€off Gโ€protein coupled receptor signaling. RGS proteins contain a characteristic RGS domain by which they interact with the ฮฑโ€subunit of Gโ€proteins and drive them into the