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Src kinase potentiates androgen receptor transactivation function and invasion of androgen-independent prostate cancer C4-2 cells

✍ Scribed by Asim, M; Siddiqui, I A; Hafeez, B B; Baniahmad, A; Mukhtar, H


Book ID
110072993
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
374 KB
Volume
27
Category
Article
ISSN
0950-9232

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## Abstract We previously demonstrated that ectopic expression of neurotrophic peptide (NP) derived from saposin C promotes androgen receptor (AR) expression and transactivation in human prostate cancer cells. This prompted us to investigate how NP or saposin C can function in cells. We constructed