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The diverse and contrasting effects of using human prostate cancer cell lines to study androgen receptor roles in prostate cancer

✍ Scribed by Yu, Sheng-Qiang; Lai, Kuo-Pao; Xia, Shu-Jie; Chang, Hong-Chiang; Chang, Chawnshang; Yeh, Shuyuan

Book ID
109832338
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
387 KB
Volume
11
Category
Article
ISSN
1008-682X

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## Abstract We previously demonstrated that ectopic expression of neurotrophic peptide (NP) derived from saposin C promotes androgen receptor (AR) expression and transactivation in human prostate cancer cells. This prompted us to investigate how NP or saposin C can function in cells. We constructed