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Inhibition of mitochondrial translation by calmodulin antagonist N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide

โœ Scribed by C Vijayasarathy; Haider Raza; Narayan G Avadhani


Book ID
115720059
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
755 KB
Volume
1143
Category
Article
ISSN
0005-2728

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Inhibition of the acrosome reaction of s
โœ Sano, Kiyoshi ๐Ÿ“‚ Article ๐Ÿ“… 1983 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 245 KB

A calmodulin antagonist, W-7 (N-(6-aminohexyl)-5-chloro-l-naphthalenesulfonamide), inhibited induction of the acrosome reaction of sea urchin spermatozoa by egg jelly at 20-50 pM, but W-5 did not. The latter, a chlorine-deficient derivative of W-7, has a lower affinity for calmodulin than does W-7.