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Clearer demonstration of calcium/calmodulin-dependent events in synaptosomes by use of the differential effects of two calmodulin antagonists, N-(aminohexyl)-5-chloro-1-naphthalenesulfonamide and N-(6-aminohexyl)-1-naphthalenesulfonamide

โœ Scribed by Imai Shizuko; Onozuka Minoru


Book ID
113379541
Publisher
Elsevier Science
Year
1988
Weight
673 KB
Volume
91
Category
Article
ISSN
0306-4492

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๐Ÿ“œ SIMILAR VOLUMES


Inhibition of the acrosome reaction of s
โœ Sano, Kiyoshi ๐Ÿ“‚ Article ๐Ÿ“… 1983 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 245 KB

A calmodulin antagonist, W-7 (N-(6-aminohexyl)-5-chloro-l-naphthalenesulfonamide), inhibited induction of the acrosome reaction of sea urchin spermatozoa by egg jelly at 20-50 pM, but W-5 did not. The latter, a chlorine-deficient derivative of W-7, has a lower affinity for calmodulin than does W-7.