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Inhibition by auranofin of pharmacologic and antigen-induced contractions of the isolated guinea pig trachea

✍ Scribed by MALO, P; WASSERMAN, M; PARRIS, D; PFEIFFER, D


Book ID
119494581
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
477 KB
Volume
77
Category
Article
ISSN
1097-6825

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Antigen (ovalbumin)-induced contraction of guinea-pig isolated trachea, which largely resulted from the endogenous release of peptidoleukotrienes, was strongly inhibited by the non-selective phosphodiesterase (PDE) inhibitor theophylline and, more potently, by the selective PDE type IV inhibitors ro