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Neurokinin A-induced contraction of guinea-pig isolated trachea: potentiation by hepoxilins

✍ Scribed by Odette Laneuville; Réjean Couture; Cecil R. Pace-Asciak

Book ID
117959791
Publisher
Nature Publishing Group
Year
1992
Tongue
English
Weight
964 KB
Volume
107
Category
Article
ISSN
0007-1188

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Antigen (ovalbumin)-induced contraction of guinea-pig isolated trachea, which largely resulted from the endogenous release of peptidoleukotrienes, was strongly inhibited by the non-selective phosphodiesterase (PDE) inhibitor theophylline and, more potently, by the selective PDE type IV inhibitors ro