The hot water extract (HWE) of the seed of Mucuna pruriens dose-dependently contracted the guinea-pig ileum. The ED 50 and pD 2 values for the HWE was lower than those of ACh and histamine. Cyproheptadine and promethazine (10 ng/mL) significantly antagonized the effects of histamine, 5-hydroxytrypta
โฆ LIBER โฆ
Neurokinin A-induced guinea pig gallbladder contraction: Potential mechanism of action
โ Scribed by Chafiq Moummi
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 444 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0272-4391
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## Abstract ## Objective Numerous reports of the induction or worsening of psoriasis in patients treated with tumor necrosis factor (TNF) antagonists indicate that this is not a rare phenomenon. The etiology of this paradoxical clinical response remains unclear. The aim of this study was to descri