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Inhibition of the antigen-induced contraction of isolated sensitized guinea pig trachea by 5,8,11,14 eicosatetraynoic acid (ETYA)

โœ Scribed by M. Hitchcock; N.A. Kokolis


Book ID
107927259
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
88 KB
Volume
2
Category
Article
ISSN
0192-0561

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Antigen (ovalbumin)-induced contraction of guinea-pig isolated trachea, which largely resulted from the endogenous release of peptidoleukotrienes, was strongly inhibited by the non-selective phosphodiesterase (PDE) inhibitor theophylline and, more potently, by the selective PDE type IV inhibitors ro