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Influence of Maternal Toxicity on the Outcome of Developmental Toxicity Studies

✍ Scribed by Paumgartten, Francisco J. R.


Book ID
118043957
Publisher
Taylor and Francis Group
Year
2010
Tongue
English
Weight
129 KB
Volume
73
Category
Article
ISSN
1087-2620

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## Abstract The role of maternal toxicity in lovastatin‐induced developmental toxicity in rats was examined in a series of studies. The first study administered lovastatin at 100, 200, 400, or 800 mg/kg/day (mkd) orally to mated rats from Gestation Day (GD) 6 through 20. Maternal toxicity was obser