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Commentary on the Role of Maternal Toxicity on Developmental Toxicity

✍ Scribed by Rochelle W. Tyl*

Book ID
112009366
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
463 KB
Volume
95
Category
Article
ISSN
1542-9733

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## Abstract The role of maternal toxicity in lovastatin‐induced developmental toxicity in rats was examined in a series of studies. The first study administered lovastatin at 100, 200, 400, or 800 mg/kg/day (mkd) orally to mated rats from Gestation Day (GD) 6 through 20. Maternal toxicity was obser