Production of human-mouse chimeric antib
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Yoshiharu Takazawa; Michiyuki Tokashiki
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Article
📅
1989
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Springer
🌐
English
⚖ 613 KB
Two mouse myeloma cell lines which were transfected with chimeric mouse variable-human constant immunoglobulin heavy and light chain genes have been cultured at high cell density in a settling perfusion culture vessel to produce chimeric antibody specific for human common acute lymphocytic leukemia