The effect of fatty acids on hybridoma cell growth and antibody productivity in serum-free cultures
โ Scribed by M. Butler; N. Huzel
- Book ID
- 119132179
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 839 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0168-1656
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๐ SIMILAR VOLUMES
The effect of serum on cell growth and monoclonal antibody (MAb) productivity was studied in a repeated fedbatch mode using both free-suspended and immobilized S3H5/y2bA2 hybridoma cells. In the suspension culture, serum influenced the cell growth rate but not the specific MAb productivity. The aver
A quantitative study of the influence of initial serum concentration on hybridoma growth rate, maximum viable and total cell yield, and specific antibody production rate is presented. The specific growth rate varied in a Monod fashion with initial serum levels (2-10ยฐ/0 FCS), giving K,,, = 1.6 v/v% a