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Effect of Bcl-2 overexpression on cell cycle and antibody productivity in chemostat cultures of myeloma NS0 cells

✍ Scribed by Beng Ti Tey; Mohamed Al-Rubeai

Book ID
115031782
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
420 KB
Volume
100
Category
Article
ISSN
1389-1723

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## Abstract We investigated the transcriptional response of NS0 cells undergoing controlled nutrient growth change in continuous chemostat culture using mouse microarrays. A 50% reduction in growth rate resulted in detectable alterations in the expression of 29 genes in NS0 cells. Notably, expressi