Overexpression of recombinant proteins in animal cells is commonly achieved by using gene amplification techniques. Gene amplified cells possess up to several thousand genes coding for the target protein. Constitutive expression of these genes leads to high levels of the corresponding mRNA species
Effects of overexpression of X-box binding protein 1 on recombinant protein production in Chinese hamster ovary and NS0 myeloma cells
β Scribed by Sebastian C.Y. Ku; Daphne T.W. Ng; Miranda G.S. Yap; Sheng-Hao Chao
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 307 KB
- Volume
- 99
- Category
- Article
- ISSN
- 0006-3592
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