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Increase of plasma adrenocorticotrophin and cortisol in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated dogs

✍ Scribed by Mutsuhiko Mizobuchi; Takashi Hineno; Yasuo Kakimoto; Katsuhiko Hiratani


Book ID
115804544
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
262 KB
Volume
612
Category
Article
ISSN
0006-8993

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## Abstract In 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine (MPTP) models of Parkinson's disease (PD), dopaminergic (DA) neurons have been shown to die by apoptosis. Moreover, recent postmortem and in vitro results have indicated that apoptotic cell death induced by 1‐methyl‐4‐phenylpyridinium (MPP