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In vivo affinity of [18F]fallypride for striatal and extrastriatal dopamine D2receptors in nonhuman primates

โœ Scribed by Mark Slifstein; Dah-Ren Hwang; Yiyun Huang; NingNing Guo; Yasuhiko Sudo; Raj Narendran; Peter Talbot; Marc Laruelle


Book ID
105880791
Publisher
Springer
Year
2004
Tongue
English
Weight
302 KB
Volume
175
Category
Article
ISSN
0033-3158

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Quantitation of striatal and extrastriat
โœ Bradley T. Christian; Tanjore K. Narayanan; Bingzhi Shi; Jogeshwar Mukherjee ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 143 KB ๐Ÿ‘ 1 views

[(18)F]Fallypride is a highly selective, high-affinity dopamine D-2 receptor ligand. The high affinity, K(D) = 30 pM, makes it a suitable candidate for visualizing both striatal and extrastriatal binding in the brain. In this work, dynamic PET studies of two macaque monkeys were acquired along with