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D2/D3 receptor binding in striatal and extrastriatal regions in schizophrenia measured with [18F]fallypride PET

✍ Scribed by Lawrence S. Kegeles; M. Slifstein; X. Xu; E. Hackett; R. Gil; B. Alvarez; E. Meyers; N. Urban; M. Laruelle; A. Abi-Dargham


Book ID
118491219
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
52 KB
Volume
41
Category
Article
ISSN
1053-8119

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[(18)F]Fallypride is a highly selective, high-affinity dopamine D-2 receptor ligand. The high affinity, K(D) = 30 pM, makes it a suitable candidate for visualizing both striatal and extrastriatal binding in the brain. In this work, dynamic PET studies of two macaque monkeys were acquired along with