In vitro malignant transformation by polyoma virus
β Scribed by Werner Kirsten
- Book ID
- 118533832
- Publisher
- Elsevier Science
- Year
- 1964
- Tongue
- English
- Weight
- 200 KB
- Volume
- 65
- Category
- Article
- ISSN
- 1097-6833
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## Abstract The transformation of cultivated hamster brain cells by polyoma virus is reported. The transformed cell line contained polyoma virusβspecific nuclear, surface and transplantation antigens. Subcutaneous and intracranial inoculations revealed high tumorigenicity of the cells. Brainβspecif
The chromosome banding pattern has been analyzed in clones of male and female golden hamster cells independently transformed by polyoma virus and tumors derived from these cells. All the tumors showed either a loss of a piece of chromosome S3 or a gain of a piece or a whole chromosome of 5,. An addi