Abortive Transformation by Polyoma Virus
β Scribed by STOKER, MICHAEL
- Book ID
- 109662531
- Publisher
- Nature Publishing Group
- Year
- 1968
- Tongue
- English
- Weight
- 809 KB
- Volume
- 218
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/218234a0
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## Abstract Abortive transformation of layer cultures of BHK 21 cells by polyoma virus has been studied using serumβdepleted medium. High doses of partially purified infectious virus, in the absence of serum, stimulate the majority of the cells to synthesize DNA while empty capsids do not. The onse
## Abstract When BHK 21 cells are exposed to high multiplicities of polyoma virus, a change in surface antigen may be detected by immunofluorescence, beginning at 18 h and affecting up to 88% of cells 24 h after infection. Timeβlapse cinematography shows that there is a concurrent change in movemen