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In vitro Cytolysis of B-Lymphoma Cells Mediated by an Anti-CD3/Anti-CD20 Bispecific Single-chain Antibody

✍ Scribed by YU, R; LI, S; WU, B; LIU, H; YE, L; LIU, X; WANG, Q; CHEN, Z

Book ID
122990809
Publisher
Elsevier Science
Year
2006
Weight
872 KB
Volume
22
Category
Article
ISSN
1872-2075

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## Abstract Trifunctional bispecific antibodies can efficiently mediate tumor cell killing by redirecting T cells and immune accessory cells to the tumor cell. Here, we describe the new trifunctional antibody, Bi20 (FBTA05, anti‐CD20 Γ— anti‐CD3), that connects B cells and T cells __via__ its variab