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Efficient inhibition of human B-cell lymphoma xenografts with an anti-CD20×anti-CD3 bispecific diabody

✍ Scribed by Dongsheng Xiong; Yuanfu Xu; Hanzhi Liu; Hui Peng; Xiaofeng Shao; Zenzu Lai; Dongmei Fan; Min Yang; Junling Han; Yong Xie; Chunzheng Yang; Zhenping Zhu


Book ID
117467159
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
209 KB
Volume
177
Category
Article
ISSN
0304-3835

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Bi20 (fBTA05), a novel trifunctional bis
✍ Michael Stanglmaier; Margot Faltin; Peter Ruf; Annette Bodenhausen; Petra Schröd 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 French ⚖ 312 KB

## Abstract Trifunctional bispecific antibodies can efficiently mediate tumor cell killing by redirecting T cells and immune accessory cells to the tumor cell. Here, we describe the new trifunctional antibody, Bi20 (FBTA05, anti‐CD20 × anti‐CD3), that connects B cells and T cells __via__ its variab