Improved synthesis of [11C]SA4503, [11C]MPDX and [11C]TMSX by use of [11C]methyl triflate
β Scribed by Kazunori Kawamura; Kiichi Ishiwata
- Publisher
- Springer Japan
- Year
- 2004
- Tongue
- English
- Weight
- 343 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0914-7187
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π SIMILAR VOLUMES
[11C]Methyl triflate ([11C]methyl trifluoromethanesulfonate) was formed in high yield when [11C]methyl iodide in a nitrogen carrier was passed at 200 degrees C through a column containing graphitized carbon impregnated with 50% by weight of silver triflate.
On-line ["Clmethylation using ["Clmethyl iodide has been successfully applied to the preparation of L-[methyl-"Clmethionine ("C-Met). ["C]Methyl iodide is first trapped in a short column that contains Porapak Q and L-homocysteine thiolactone coated on inert support. The column is then charged with N