Hyperpolarized 129Xe T1 in oxygenated and deoxygenated blood
β Scribed by Mitchell S. Albert; Dilip Balamore; Daniel F. Kacher; Arvind K. Venkatesh; Ferenc A. Jolesz
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 183 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0952-3480
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π SIMILAR VOLUMES
In previous experiments by the authors, in which hyperpolarized 129 Xe was dissolved in fresh blood samples, the T 1 was found to be strongly dependent on the oxygenation level, the values increasing with oxygenation: T 1 was about 4 s in deoxygenated samples and about 13 s in oxygenated samples. C.
Optically enhanced NMR with 129 Xe and 3 He is emerging as a novel and promising technique for medical imaging of lungs and other tissues. Here it is shown that hyperpolarized 129 Xe NMR provides a powerful means of measuring blood oxygenation quantitatively and noninvasively. The interaction of xen
## Abstract The first in vivo hyperpolarized ^129^Xe NMR study in experimental tumors is presented. Hyperpolarized ^129^Xe was dissolved in solutions, and was injected intratumorally in GHβ3 prolactinomas in rats and RIFβ1 fibrosarcomas in mice. The ^129^Xe NMR spectra and apparent spinβlattice rel
## Abstract Hyperpolarized ^129^Xe has been used to obtain gas phase images of mouse lung __in vivo__, showing distinct ventilation variation as a function of the breathing cycle. Spectra of ^129^Xe in the thorax show complex structure in both the gas phase (β4 to 3 ppm) and tissueβdissolved (190β2
## Abstract MR imaging of hyperpolarized (HP) nuclei is challenging because they are typically delivered in a single dose of nonrenewable magnetization, from which the entire image must be derived. This problem can be overcome with HP ^129^Xe, which can be produced sufficiently rapidly to deliver i