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Hydroxylation of Salicylate and Phenylalanine as Assays for Hydroxyl Radicals: a Cautionary Note Visited for the Third Time

✍ Scribed by Hallwell, Barry; Kaur, Harparkash

Book ID
124159684
Publisher
Informa plc
Year
1997
Tongue
English
Weight
605 KB
Volume
27
Category
Article
ISSN
1071-5762

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πŸ“œ SIMILAR VOLUMES

Aromatic hydroxylation of phenylalanine
Aromatic hydroxylation of phenylalanine as an assay for hydroxyl radicals: Application to activated human neutrophils and to the heme protein leghemoglobin
✍ Harparkash Kaur; Ingrid Fagerheim; Martin Grootveld; Alain Puppo; Barry Halliwel πŸ“‚ Article πŸ“… 1988 πŸ› Elsevier Science 🌐 English βš– 650 KB

Attack of hydroxyl radical (.OH), generated by a Fenton system at physiological pH, upon L-phenylalanine produces three isomeric tyrosines, o-tyrosine (2-hydroxyphenylalanine), m-tyrosine (3-hydroxyphenylalanine), and p-tyrosine (4-hydroxyphenylalanine). These may be separated by high-performance li