Aromatic hydroxylation of phenylalanine
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Harparkash Kaur; Ingrid Fagerheim; Martin Grootveld; Alain Puppo; Barry Halliwel
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Article
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1988
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Elsevier Science
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English
β 650 KB
Attack of hydroxyl radical (.OH), generated by a Fenton system at physiological pH, upon L-phenylalanine produces three isomeric tyrosines, o-tyrosine (2-hydroxyphenylalanine), m-tyrosine (3-hydroxyphenylalanine), and p-tyrosine (4-hydroxyphenylalanine). These may be separated by high-performance li