𝔖 Bobbio Scriptorium
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Hsp90: A Drug Target?

✍ Scribed by Jeffrey M. Holzbeierlein; Andrew Windsperger; George Vielhauer

Book ID
107546734
Publisher
Current Science Inc.
Year
2010
Tongue
English
Weight
123 KB
Volume
12
Category
Article
ISSN
1523-3790

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## Abstract The modulation of DNA topology by topoisomerase II plays a crucial role during chromosome condensation and segregation in mitosis and has thus become a highly attractive target for chemotherapeutic drugs. However, these drugs are highly toxic, and so new approaches are required. One suc