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Complexity of Hsp90 in organelle targeting

✍ Scribed by Constantinos Prassinos; Kosmas Haralampidis; Dimitra Milioni; Despina Samakovli; Konstantinos Krambis; Polydefkis Hatzopoulos

Book ID
106498232
Publisher
Springer
Year
2008
Tongue
English
Weight
552 KB
Volume
67
Category
Article
ISSN
0167-4412

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## Abstract The modulation of DNA topology by topoisomerase II plays a crucial role during chromosome condensation and segregation in mitosis and has thus become a highly attractive target for chemotherapeutic drugs. However, these drugs are highly toxic, and so new approaches are required. One suc