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Targeting multiple signal transduction pathways through inhibition of Hsp90

โœ Scribed by Hong Zhang; Francis Burrows


Publisher
Springer
Year
2004
Tongue
English
Weight
382 KB
Volume
82
Category
Article
ISSN
0946-2716

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## Abstract The Cbfa1/Runx2 is an important transcription factor necessary for osteoblast differentiation and bone formation. However, the signaling pathways regulating Runx2 activity are just beginning to be understood. Inconsistencies between Runx2 mRNA or protein levels and its transcriptional a