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Effects of inhibiting JAK on invasion and metastasis of the human breast cancer cells through ERK signaling transduction pathway

✍ Scribed by Jing Zhao; Hong-fang Chen; Hua-yu Deng


Publisher
Chinese Anti-Cancer Association
Year
2009
Tongue
English
Weight
406 KB
Volume
21
Category
Article
ISSN
1000-9604

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Effects of tyrosine kinase inhibitors on
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Breast cancers frequently over-express a number of growth factor receptors. In addition, elevated src family kinase activity is present in a percentage of these neoplasms and has been implicated in signal transduction in these cells. Therefore, inhibiting tyrosine kinase activity is a potential appr