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Histone deacetylase inhibitors: new drugs for the treatment of inflammatory diseases?

✍ Scribed by Frédéric Blanchard; Céline Chipoy

Book ID
114384935
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
193 KB
Volume
10
Category
Article
ISSN
1359-6446

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## Abstract Histone deacetylases (HDACs) are involved in chromatin remodeling and modification of nonhistone transcription regulatory proteins, thus modulating the expression of genes important for complex biological events. Dysregulation of HDACs and aberrant chromatin acetylation and deacetylatio