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Histone deacetylase inhibitors: a new and promising drug class for the treatment of arthritis?

✍ Scribed by Éric Toussirot; Kashif Aziz Khan; Georges Herbein

Book ID
107687346
Publisher
Springer-Verlag
Year
2010
Tongue
English
Weight
99 KB
Volume
1
Category
Article
ISSN
1868-7075

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## Abstract Histone deacetylase (HDAC) inhibitors, such as valproic acid (VPA), constitute a novel class of anticancer agents that cause an increase in acetylated histones and thus restore the expression of dormant tumor‐suppressor and other genes related to cell differentiation, cell‐cycle arrest