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HISTONE-DEACETYLASE INHIBITORS: NOVEL DRUGS FOR THE TREATMENT OF CANCER

✍ Scribed by Johnstone, Ricky W.


Book ID
109951433
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
812 KB
Volume
1
Category
Article
ISSN
1474-1776

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## Abstract Histone deacetylases (HDACs) are involved in chromatin remodeling and modification of nonhistone transcription regulatory proteins, thus modulating the expression of genes important for complex biological events. Dysregulation of HDACs and aberrant chromatin acetylation and deacetylatio