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Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer

✍ Scribed by Minucci, Saverio; Pelicci, Pier Giuseppe

Book ID
109947538
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
522 KB
Volume
6
Category
Article
ISSN
1474-1776

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## Abstract Histone deacetylases (HDACs) are involved in chromatin remodeling and modification of nonhistone transcription regulatory proteins, thus modulating the expression of genes important for complex biological events. Dysregulation of HDACs and aberrant chromatin acetylation and deacetylatio