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Histone deacetylase inhibitors, anticancerous mechanism and therapy for gastrointestinal cancers

โœ Scribed by JING YUAN FANG

Book ID
108950268
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
86 KB
Volume
20
Category
Article
ISSN
0815-9319

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## Abstract Histone deacetylase (HDAC) inhibitors, such as valproic acid (VPA), constitute a novel class of anticancer agents that cause an increase in acetylated histones and thus restore the expression of dormant tumorโ€suppressor and other genes related to cell differentiation, cellโ€cycle arrest