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Histone deacetylase inhibitors: Keeping momentum for neuromuscular and cardiovascular diseases treatment

✍ Scribed by Claudia Colussi; Barbara Illi; Jessica Rosati; Francesco Spallotta; Antonella Farsetti; Annalisa Grasselli; Antonello Mai; Maurizio C. Capogrossi; Carlo Gaetano

Book ID
119346759
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
539 KB
Volume
62
Category
Article
ISSN
1043-6618

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## Abstract Histone deacetylases (HDACs) are involved in chromatin remodeling and modification of nonhistone transcription regulatory proteins, thus modulating the expression of genes important for complex biological events. Dysregulation of HDACs and aberrant chromatin acetylation and deacetylatio