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Highly Concise Routes to Epothilones: The Total Synthesis and Evaluation of Epothilone 490

โœ Scribed by Biswas, Kaustav; Lin, Hong; Njardarson, Jon T.; Chappell, Mark D.; Chou, Ting-Chao; Guan, Yongbiao; Tong, William P.; He, Lifeng; Horwitz, Susan B.; Danishefsky, Samuel J.


Book ID
121418011
Publisher
American Chemical Society
Year
2002
Tongue
English
Weight
220 KB
Volume
124
Category
Article
ISSN
0002-7863

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ChemInform Abstract: Synthesis of Epothi
โœ D. SCHINZER; A. BAUER; J. SCHIEBER ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 25 KB ๐Ÿ‘ 1 views

## Synthesis of Epothilones: Stereoselective Routes to Epothilone B. -In continuation of studies concerning the total synthesis of epothilones, efficient routes to epothilone B (I) using a macro-lactonization and a metathesis approach are detailed.