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Highly Concise Routes to Epothilones: The Total Synthesis and Evaluation of Epothilone 490.

โœ Scribed by Kaustav Biswas; Hong Lin; Jon T. Njardarson; Mark D. Chappell; Ting-Chao Chou; Yongbiao Guan; William P. Tong; Lifeng He; Susan B. Horwitz; Samuel J. Danishefsky


Publisher
John Wiley and Sons
Year
2010
Weight
28 KB
Volume
33
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Synthesis of Epothi
โœ D. SCHINZER; A. BAUER; J. SCHIEBER ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 25 KB ๐Ÿ‘ 1 views

## Synthesis of Epothilones: Stereoselective Routes to Epothilone B. -In continuation of studies concerning the total synthesis of epothilones, efficient routes to epothilone B (I) using a macro-lactonization and a metathesis approach are detailed.