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ChemInform Abstract: Probing the Ring Size of Epothilones: Total Synthesis of [14]-, [15]-, [17]-, and [18]Epothilones A.

✍ Scribed by K. C. NICOLAOU; F. SARABIA; S. NINKOVIC; M. R. V. FINLAY; C. N. C. BODDY

Publisher: John Wiley and Sons
Year: 2010
Weight: 28 KB
Volume: 29
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199818205

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Total Synthesis of Epothilone A: The Olefin Metathesis Approach. -Starting with the three building blocks (I)-(III) the coupling product (IV) is obtained. It is used for olefin metathesis as the key step in the synthesis of the title compound (VI). -(YANG, Z.;