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ChemInform Abstract: Synthesis of Epothilones: Stereoselective Routes to Epothilone B.

✍ Scribed by D. SCHINZER; A. BAUER; J. SCHIEBER

Publisher: John Wiley and Sons
Year: 2010
Weight: 25 KB
Volume: 29
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199846268

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✦ Synopsis

Synthesis of Epothilones: Stereoselective Routes to Epothilone B.

-In continuation of studies concerning the total synthesis of epothilones, efficient routes to epothilone B (I) using a macro-lactonization and a metathesis approach are detailed.

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