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High specific activity labelling of some tricyclic antidepressants

✍ Scribed by O. Buchman; I. Pri-Bar

Publisher
John Wiley and Sons
Year
1978
Tongue
French
Weight
244 KB
Volume
14
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

Activated palladium is used as catalyst for the hydrogen‐tritium exchange in tricyclic antidepressants. The specific activities obtained are: desipramine: 44.9 Ci/mmol; imipramine: 14.9 Ci/mmol; notriptyline: 2.0 Ci/mmol and amitriptyline: 1.7 Ci/mmol.

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