Hexafluoroacetone as Protecting and Activating Reagent: Site-Selective Functionalization of α-Amino Alkanedioic Acids.
✍ Scribed by Thomas Ruehl; Christoph Boettcher; Ksenia Pumpor; Lothar Henning; Joachim Sieler; Klaus Burger
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 34 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
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📜 SIMILAR VOLUMES
## Abstract The synthesis of heterocyclic α‐mercapto acids starting from (__RS__)‐thiomalic acid using hexafluoroacetone as protecting and activating agent is described. The new compounds are useful building blocks for peptide and depsipeptide modification as well as for drug design.
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