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Synthesis of Heteroaryl Substituted α-Mercapto Acids from Thiomalic Acid Using Hexafluoroacetone as Protecting and Activating Reagent.

✍ Scribed by Ksenia Pumpor; Elisabeth Windeisen; Klaus Burger

Publisher
John Wiley and Sons
Year
2003
Weight
155 KB
Volume
34
Category
Article
ISSN
0931-7597

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Synthesis of heteroaryl substituted α-me
Synthesis of heteroaryl substituted α-mercapto acids from thiomalic acid using hexafluoroacetone as protecting and activating reagent
✍ Ksenia Pumpor; Elisabeth Windeisen; Klaus Burger 📂 Article 📅 2003 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 99 KB

## Abstract The synthesis of heterocyclic α‐mercapto acids starting from (__RS__)‐thiomalic acid using hexafluoroacetone as protecting and activating agent is described. The new compounds are useful building blocks for peptide and depsipeptide modification as well as for drug design.