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Herpes Simplex Virus Clearance during Purification of a Recombinant Adeno-associated Virus Serotype 1 Vector

✍ Scribed by Ye, Guo-jie; Scotti, Marina M; Thomas, Darby L; Wang, Lijun; Knop, David R.; Chulay, Jeffrey David

Book ID: 127246635
Publisher: Mary Ann Liebert
Year: 2014
Tongue: English
Weight: 439 KB
Category: Article
ISSN: 2324-8637
DOI: 10.1089/hum.2014.060

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## Abstract ## Background The development of stable producer cell lines for recombinant adeno‐associated virus (rAAV) assembly is a strategy followed by many groups to develop scalable production methods suitable for good manufacturing practice (GMP) requirements. The major drawback of this method