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Identification of a replication-defective herpes simplex virus for recombinant adeno-associated virus type 2 (rAAV2) particle assembly using stable producer cell lines

✍ Scribed by Estelle Toublanc; Abdellatif Benraiss; Delphine Bonnin; Véronique Blouin; Nicole Brument; Nathalie Cartier; Alberto L. Epstein; Philippe Moullier; Anna Salvetti


Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
387 KB
Volume
6
Category
Article
ISSN
1099-498X

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Identification of a replication-defectiv
✍ Estelle Toublanc; Abdellatif Benraiss; Delphine Bonnin; Véronique Blouin; Nicole 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 387 KB

## Abstract ## Background The development of stable producer cell lines for recombinant adeno‐associated virus (rAAV) assembly is a strategy followed by many groups to develop scalable production methods suitable for good manufacturing practice (GMP) requirements. The major drawback of this method