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Generation of a recombinant herpes simplex virus which can provide packaging function for recombinant adeno-associated virus

✍ Scribed by Zhijian Wu; Xiaobing Wu; Yunde Hou

Book ID: 105652399
Publisher: Springer
Year: 1999
Tongue: English
Weight: 337 KB
Volume: 44
Category: Article
ISSN: 1001-6538
DOI: 10.1007/bf02909710

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## Abstract ## Background The development of stable producer cell lines for recombinant adeno‐associated virus (rAAV) assembly is a strategy followed by many groups to develop scalable production methods suitable for good manufacturing practice (GMP) requirements. The major drawback of this method