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PEG-modulated column chromatography for purification of recombinant adeno-associated virus serotype 9

✍ Scribed by Jingmin Zhou; Xiao Yang; J. Fraser Wright; Katherine A. High; Linda Couto; Guang Qu


Book ID
113768604
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
865 KB
Volume
173
Category
Article
ISSN
0166-0934

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## Abstract ## Background Cardiac gene transfer may serve as a novel therapeutic approach for heart disease. Numerous serotypes of recombinant adeno‐associated virus (rAAV) have been identified with variable tropisms to cardiac tissue. ## Methods Both __in vitro__ and __in vivo__ experiments wer