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Haplotype analysis of TP53 polymorphisms, Arg72Pro and Ins16, in BRCA1 and BRCA2 mutation carriers of French Canadian descent

✍ Scribed by Luca Cavallone; Suzanna L Arcand; Christine Maugard; Parviz Ghadirian; Anne-Marie Mes-Masson; Diane Provencher; Patricia N Tonin


Book ID
115011511
Publisher
BioMed Central
Year
2008
Tongue
English
Weight
389 KB
Volume
8
Category
Article
ISSN
1471-2407

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## Communicated by Dvorah Abeliovich Germline mutations in the BRCA1 and BRCA2 genes confer a high lifetime risk of developing breast and other cancers; however, remarkable differences exist regarding disease manifestation in mutation carriers. It has been suggested that other genetic and/or enviro